Antibody data
- Antibody Data
- Antigen structure
- References [22]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 10762-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10762-1-AP, RRID:AB_2074898
- Product name
- CDK1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated CDK1 antibody (Cat. #10762-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: FC, IF, IHC, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Inhibitory Effects of Periplocin on Lymphoma Cells: A Network Pharmacology Approach and Experimental Validation.
Pinocembrin Inhibits the Proliferation and Metastasis of Breast Cancer via Suppression of the PI3K/AKT Signaling Pathway.
Therapeutic Targeting PLK1 by ON-01910.Na Is Effective in Local Treatment of Retinoblastoma.
Bioinformatics analysis combined with experiments predicts CENPK as a potential prognostic factor for lung adenocarcinoma.
MicroRNA-520c-3p targeting of RelA/p65 suppresses atherosclerotic plaque formation.
The ATPase Pontin is a key cell cycle regulator by amplifying E2F1 transcription response in glioma.
Solasonine Suppresses the Proliferation of Acute Monocytic Leukemia Through the Activation of the AMPK/FOXO3A Axis.
Extracellular Vesicle Delivery of TRAIL Eradicates Resistant Tumor Growth in Combination with CDK Inhibition by Dinaciclib.
Osthole induces cell cycle arrest and apoptosis in head and neck squamous cell carcinoma by suppressing the PI3K/AKT signaling pathway.
Nuciferine inhibits the progression of glioblastoma by suppressing the SOX2-AKT/STAT3-Slug signaling pathway.
CtIP promotes G2/M arrest in etoposide-treated HCT116 cells in a p53-independent manner.
Metformin Treatment Suppresses Melanoma Cell Growth and Motility Through Modulation of microRNA Expression.
EPB41L3 is a potential tumor suppressor gene and prognostic indicator in esophageal squamous cell carcinoma.
Osthole inhibits the PI3K/AKT signaling pathway via activation of PTEN and induces cell cycle arrest and apoptosis in esophageal squamous cell carcinoma.
Proteasome Inhibitor Carbobenzoxy-L-Leucyl-L-Leucyl-L-Leucinal (MG132) Enhances Therapeutic Effect of Paclitaxel on Breast Cancer by Inhibiting Nuclear Factor (NF)-κB Signaling.
The aryl hydrocarbon receptor and interferon gamma generate antiviral states via transcriptional repression.
PFKFB3 blockade inhibits hepatocellular carcinoma growth by impairing DNA repair through AKT.
Whole exome-wide association study identifies a missense variant in SLC2A4RG associated with glioblastoma risk.
Synergistic antitumor effect of 3-bromopyruvate and 5-fluorouracil against human colorectal cancer through cell cycle arrest and induction of apoptosis.
1, 25(OH)2D3-induced interaction of vitamin D receptor with p50 subunit of NF-κB suppresses the interaction between KLF5 and p50, contributing to inhibition of LPS-induced macrophage proliferation.
Elevated GAPDH expression is associated with the proliferation and invasion of lung and esophageal squamous cell carcinomas.
Novel taspine derivative 12k inhibits cell growth and induces apoptosis in lung cell carcinoma.
Zhao R, Han C, Dai S, Wei S, Xiang X, Wang Y, Zhao R, Zhao L, Shan B
Drug design, development and therapy 2021;15:1333-1344
Drug design, development and therapy 2021;15:1333-1344
Pinocembrin Inhibits the Proliferation and Metastasis of Breast Cancer via Suppression of the PI3K/AKT Signaling Pathway.
Zhu X, Li R, Wang C, Zhou S, Fan Y, Ma S, Gao D, Gai N, Yang J
Frontiers in oncology 2021;11:661184
Frontiers in oncology 2021;11:661184
Therapeutic Targeting PLK1 by ON-01910.Na Is Effective in Local Treatment of Retinoblastoma.
Ma H, Nie C, Chen Y, Li J, Xie Y, Tang Z, Gao Y, Ai S, Mao Y, Sun Q, Lu R
Oncology research 2021 Sep 7;28(7):745-761
Oncology research 2021 Sep 7;28(7):745-761
Bioinformatics analysis combined with experiments predicts CENPK as a potential prognostic factor for lung adenocarcinoma.
Ma J, Chen X, Lin M, Wang Z, Wu Y, Li J
Cancer cell international 2021 Jan 21;21(1):65
Cancer cell international 2021 Jan 21;21(1):65
MicroRNA-520c-3p targeting of RelA/p65 suppresses atherosclerotic plaque formation.
Wang J, Hu X, Hu X, Gao F, Li M, Cui Y, Wei X, Qin Y, Zhang C, Zhao Y, Gao Y
The international journal of biochemistry & cell biology 2021 Feb;131:105873
The international journal of biochemistry & cell biology 2021 Feb;131:105873
The ATPase Pontin is a key cell cycle regulator by amplifying E2F1 transcription response in glioma.
Wang R, Li X, Sun C, Yu L, Hua D, Shi C, Wang Q, Rao C, Luo W, Jiang Z, Zhou X, Yu S
Cell death & disease 2021 Feb 1;12(2):141
Cell death & disease 2021 Feb 1;12(2):141
Solasonine Suppresses the Proliferation of Acute Monocytic Leukemia Through the Activation of the AMPK/FOXO3A Axis.
Zhang H, Tian F, Jiang P, Qian S, Dai X, Ma B, Wang M, Dai H, Sha X, Yang Z, Zhu X, Sun X
Frontiers in oncology 2020;10:614067
Frontiers in oncology 2020;10:614067
Extracellular Vesicle Delivery of TRAIL Eradicates Resistant Tumor Growth in Combination with CDK Inhibition by Dinaciclib.
Ke C, Hou H, Li J, Su K, Huang C, Lin Y, Lu Z, Du Z, Tan W, Yuan Z
Cancers 2020 May 4;12(5)
Cancers 2020 May 4;12(5)
Osthole induces cell cycle arrest and apoptosis in head and neck squamous cell carcinoma by suppressing the PI3K/AKT signaling pathway.
Yang J, Zhu XJ, Jin MZ, Cao ZW, Ren YY, Gu ZW
Chemico-biological interactions 2020 Jan 25;316:108934
Chemico-biological interactions 2020 Jan 25;316:108934
Nuciferine inhibits the progression of glioblastoma by suppressing the SOX2-AKT/STAT3-Slug signaling pathway.
Li Z, Chen Y, An T, Liu P, Zhu J, Yang H, Zhang W, Dong T, Jiang J, Zhang Y, Jiang M, Yang X
Journal of experimental & clinical cancer research : CR 2019 Mar 29;38(1):139
Journal of experimental & clinical cancer research : CR 2019 Mar 29;38(1):139
CtIP promotes G2/M arrest in etoposide-treated HCT116 cells in a p53-independent manner.
Chen H, Shan J, Chen D, Wang R, Qi W, Wang H, Ke Y, Liu W, Zeng X
Journal of cellular physiology 2019 Jul;234(7):11871-11881
Journal of cellular physiology 2019 Jul;234(7):11871-11881
Metformin Treatment Suppresses Melanoma Cell Growth and Motility Through Modulation of microRNA Expression.
Tseng HW, Li SC, Tsai KW
Cancers 2019 Feb 11;11(2)
Cancers 2019 Feb 11;11(2)
EPB41L3 is a potential tumor suppressor gene and prognostic indicator in esophageal squamous cell carcinoma.
Zeng R, Liu Y, Jiang ZJ, Huang JP, Wang Y, Li XF, Xiong WB, Wu XC, Zhang JR, Wang QE, Zheng YF
International journal of oncology 2018 May;52(5):1443-1454
International journal of oncology 2018 May;52(5):1443-1454
Osthole inhibits the PI3K/AKT signaling pathway via activation of PTEN and induces cell cycle arrest and apoptosis in esophageal squamous cell carcinoma.
Zhu X, Li Z, Li T, Long F, Lv Y, Liu L, Liu X, Zhan Q
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jun;102:502-509
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jun;102:502-509
Proteasome Inhibitor Carbobenzoxy-L-Leucyl-L-Leucyl-L-Leucinal (MG132) Enhances Therapeutic Effect of Paclitaxel on Breast Cancer by Inhibiting Nuclear Factor (NF)-κB Signaling.
Zhang Y, Yang B, Zhao J, Li X, Zhang L, Zhai Z
Medical science monitor : international medical journal of experimental and clinical research 2018 Jan 15;24:294-304
Medical science monitor : international medical journal of experimental and clinical research 2018 Jan 15;24:294-304
The aryl hydrocarbon receptor and interferon gamma generate antiviral states via transcriptional repression.
Kueck T, Cassella E, Holler J, Kim B, Bieniasz PD
eLife 2018 Aug 22;7
eLife 2018 Aug 22;7
PFKFB3 blockade inhibits hepatocellular carcinoma growth by impairing DNA repair through AKT.
Shi WK, Zhu XD, Wang CH, Zhang YY, Cai H, Li XL, Cao MQ, Zhang SZ, Li KS, Sun HC
Cell death & disease 2018 Apr 1;9(4):428
Cell death & disease 2018 Apr 1;9(4):428
Whole exome-wide association study identifies a missense variant in SLC2A4RG associated with glioblastoma risk.
Zhao Y, Yun D, Zou X, Jiang T, Li G, Hu L, Chen J, Xu J, Mao Y, Chen H, Lu D
American journal of cancer research 2017;7(9):1937-1947
American journal of cancer research 2017;7(9):1937-1947
Synergistic antitumor effect of 3-bromopyruvate and 5-fluorouracil against human colorectal cancer through cell cycle arrest and induction of apoptosis.
Chong D, Ma L, Liu F, Zhang Z, Zhao S, Huo Q, Zhang P, Zheng H, Liu H
Anti-cancer drugs 2017 Sep;28(8):831-840
Anti-cancer drugs 2017 Sep;28(8):831-840
1, 25(OH)2D3-induced interaction of vitamin D receptor with p50 subunit of NF-κB suppresses the interaction between KLF5 and p50, contributing to inhibition of LPS-induced macrophage proliferation.
Ma D, Zhang RN, Wen Y, Yin WN, Bai D, Zheng GY, Li JS, Zheng B, Wen JK
Biochemical and biophysical research communications 2017 Jan 8;482(2):366-374
Biochemical and biophysical research communications 2017 Jan 8;482(2):366-374
Elevated GAPDH expression is associated with the proliferation and invasion of lung and esophageal squamous cell carcinomas.
Hao L, Zhou X, Liu S, Sun M, Song Y, Du S, Sun B, Guo C, Gong L, Hu J, Guan H, Shao S
Proteomics 2015 Sep;15(17):3087-100
Proteomics 2015 Sep;15(17):3087-100
Novel taspine derivative 12k inhibits cell growth and induces apoptosis in lung cell carcinoma.
Dai B, Wang W, Liu R, Wang H, Zhang Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2015 Mar;70:227-33
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2015 Mar;70:227-33
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The CDK1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human CDK1. This antibody recognizes human antigen. The CDK1 antibody has been validated for the following applications: ELISA, WB analysis.