Antibody data
- Antibody Data
- Antigen structure
- References [8]
- Comments [0]
- Validations [0]
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- Product number
- 2211 - Provider product page
- Provider
- Cell Signaling Technology, Inc
- Proper citation
- Cell Signaling Technology Cat#2211, RRID:AB_331679
- Product name
- Phospho-S6 Ribosomal Protein (Ser235/236) Antibody
- Antibody type
- Polyclonal
- Reactivity
- Human, Mouse, Rat, Simian, Yeast
- Host
- Rabbit
- Storage
- -20°C
Submitted references Exploiting cancer cell vulnerabilities to develop a combination therapy for ras-driven tumors.
Perifosine and CCI 779 co-operate to induce cell death and decrease proliferation in PTEN-intact and PTEN-deficient PDGF-driven murine glioblastoma.
Pharmacological and genetic evaluation of proposed roles of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase (MEK), extracellular signal-regulated kinase (ERK), and p90(RSK) in the control of mTORC1 protein signaling by phorbol esters.
Analysis of the phosphatidylinositol 3'-kinase signaling pathway in glioblastoma patients in vivo.
Rheb binds tuberous sclerosis complex 2 (TSC2) and promotes S6 kinase activation in a rapamycin- and farnesylation-dependent manner.
Activated mammalian target of rapamycin pathway in the pathogenesis of tuberous sclerosis complex renal tumors.
Amino acid-induced translation of TOP mRNAs is fully dependent on phosphatidylinositol 3-kinase-mediated signaling, is partially inhibited by rapamycin, and is independent of S6K1 and rpS6 phosphorylation.
Enhanced sensitivity of PTEN-deficient tumors to inhibition of FRAP/mTOR.
De Raedt T, Walton Z, Yecies JL, Li D, Chen Y, Malone CF, Maertens O, Jeong SM, Bronson RT, Lebleu V, Kalluri R, Normant E, Haigis MC, Manning BD, Wong KK, Macleod KF, Cichowski K
Cancer cell 2011 Sep 13;20(3):400-13
Cancer cell 2011 Sep 13;20(3):400-13
Perifosine and CCI 779 co-operate to induce cell death and decrease proliferation in PTEN-intact and PTEN-deficient PDGF-driven murine glioblastoma.
Pitter KL, Galbán CJ, Galbán S, Tehrani OS, Li F, Charles N, Bradbury MS, Becher OJ, Chenevert TL, Rehemtulla A, Ross BD, Holland EC, Hambardzumyan D
PloS one 2011 Jan 18;6(1):e14545
PloS one 2011 Jan 18;6(1):e14545
Pharmacological and genetic evaluation of proposed roles of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase (MEK), extracellular signal-regulated kinase (ERK), and p90(RSK) in the control of mTORC1 protein signaling by phorbol esters.
Fonseca BD, Alain T, Finestone LK, Huang BP, Rolfe M, Jiang T, Yao Z, Hernandez G, Bennett CF, Proud CG
The Journal of biological chemistry 2011 Aug 5;286(31):27111-22
The Journal of biological chemistry 2011 Aug 5;286(31):27111-22
Analysis of the phosphatidylinositol 3'-kinase signaling pathway in glioblastoma patients in vivo.
Choe G, Horvath S, Cloughesy TF, Crosby K, Seligson D, Palotie A, Inge L, Smith BL, Sawyers CL, Mischel PS
Cancer research 2003 Jun 1;63(11):2742-6
Cancer research 2003 Jun 1;63(11):2742-6
Rheb binds tuberous sclerosis complex 2 (TSC2) and promotes S6 kinase activation in a rapamycin- and farnesylation-dependent manner.
Castro AF, Rebhun JF, Clark GJ, Quilliam LA
The Journal of biological chemistry 2003 Aug 29;278(35):32493-6
The Journal of biological chemistry 2003 Aug 29;278(35):32493-6
Activated mammalian target of rapamycin pathway in the pathogenesis of tuberous sclerosis complex renal tumors.
Kenerson HL, Aicher LD, True LD, Yeung RS
Cancer research 2002 Oct 15;62(20):5645-50
Cancer research 2002 Oct 15;62(20):5645-50
Amino acid-induced translation of TOP mRNAs is fully dependent on phosphatidylinositol 3-kinase-mediated signaling, is partially inhibited by rapamycin, and is independent of S6K1 and rpS6 phosphorylation.
Tang H, Hornstein E, Stolovich M, Levy G, Livingstone M, Templeton D, Avruch J, Meyuhas O
Molecular and cellular biology 2001 Dec;21(24):8671-83
Molecular and cellular biology 2001 Dec;21(24):8671-83
Enhanced sensitivity of PTEN-deficient tumors to inhibition of FRAP/mTOR.
Neshat MS, Mellinghoff IK, Tran C, Stiles B, Thomas G, Petersen R, Frost P, Gibbons JJ, Wu H, Sawyers CL
Proceedings of the National Academy of Sciences of the United States of America 2001 Aug 28;98(18):10314-9
Proceedings of the National Academy of Sciences of the United States of America 2001 Aug 28;98(18):10314-9
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